Medically Challenged Community

EPSTEIN BARR DISEASE

The Epstein-Barr virus is responsible for infectious mononucleosis syndrome and is also closely associated to several types of cancer. The main complication involving Epstein-Barr virus infection, both in recipients of hematopoietic stem cells and solid organs, is post-transplant lymphoproliferative disease. The importance of this disease has increased interest in the development of laboratory tools to improve post-transplant monitoring and to detect the disease before clinical evolution. Viral load analysis for Epstein-Barr virus through real-time polymerase chain reaction is, at present, the best tool to measure viral load. However, there is not a consensus on which sample type is the best for the test and what is its predictive value for therapeutic interventions.

WHAT IS EPSTEIN BARR DISEASE

Epstein-Barr virus (EBV) is classified in the family Herpesviridae, subfamily Gamaherpesvirinae, genus Lymphocryptovirusand species Human herpesvirus Sequencing-based studies revealed the existence of two types of EBV.It is estimated that this ubiquitous virus has infected more than 90% of the world's population.According to the Center for Disease Control and Prevention (Atlanta, USA), 95% of the adult population between the ages of 35 and 40 are carriers of EBV.

 

EBV transmission occurs mainly through contact with oropharyngeal secretions containing the virus.Nevertheless, it can also take place through blood and blood derivative transfusions and through organ and tissue transplantation.Breast milk may also contain the virus, but this is an uncommon route of vertical transmission.Additionally, EBV is also present in genital tract secretions.

.In developing countries, primary EBV infection usually happens during childhood in an asymptomatic or clinically non-specific manner.(15) In developed countries, however, it is more common for the primary infection to occur during adolescence or adulthood, and can result in the development of classical symptoms of infectious mononucleosis syndrome (IM).(13) Studies suggest that this may be explained by the amount of virus introduced in the body.(2)

In this review, the main diseases associated with EBV, the importance of measuring post-transplant viral load by polymerase chain reaction (PCR) and the differences found in the various transplantation types were assessed...in a concise manner.

EPSTEIN BARR & RELATED DISEASES

Infectious mononucleosis I.M. usually occurs during adolescence or adulthood but can occasionally affect children and the elderly.(4) Also known as the "kissing disease",(16) it is commonly a selflimiting disease, which means it evolves to a cure without specific treatment. In 80% of the cases, there is the presence of heterophile antibodies.(9) Also, in the complete blood count, it is possible to see leukocytosis with high lymphocytosis and the presence of Downey cells (atypical lymphocytes). These lymphocytes have an enlarged cytoplasm and condensed nucleus. They are primarily T cells acting on the eradication of B cells infected by EBV.(17)

HODGKINS LYMPHOMA

There is a strong association between Hodgkin's lymphoma (HL) and EBV infection, although its role in this disease's pathogenesis is not fully clarified. The virus has been found in around 40% of HL tumors.(18) Cases in children and the elderly are generally associated with EBV, while adults with HL are more frequently EBV-negative.(19)

The histological diagnosis differs from that of other lymphomas because it shows mononuclear Hodgkin's cells and their multinuclear variants known as Reed-Sternberg cells.(19) These two cell types are derived, in the majority of cases, from B cells.

Plasmatic viral load can be quantified in virtually all EBV-positive HL patients before treatment and the response to therapy is associated to the reduction in viral load.(18) These data suggest that the analysis of plasmatic DNA through real-time PCR is an excellent tool for the prognosis and monitoring of HL patients.(2)

NON-HODGKINS LYMPHOMA

Although overall non-Hodgkin lymphoma (NHL) rates are high, there is a great variety of types of these lymphomas and a variation of incidence between countries. In general, only 5% of the tumors are EBV-positive. This ratio rises up to 40%, however, in AIDS-related cases.(20) Enlarged cervical, axillary and/or inguinal ganglia, excessive nocturnal sudoresis, fever, itchy skin and weight loss without apparent reason must be investigated

What Is Cancer

Cancer is the name given to a collection of related diseases. In all types of cancer, some of the body’s cells begin to divide without stopping and spread into surrounding tissues.

Breast Implant Disease

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Diabetes & Insulin Resistance

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Hair Loss

With so much Hair loss on the rise, we are committed to providing whole hair health services and treatments to patients with autoimmune and impulsive control disorders. We provide a physical and web-based retail ” Whole Body Service Center” In Arizona to provide health and beauty services and holistic products to clients internationally.

A.S.I.A.

Women with silicone breast implants and autoimmune inflammatory syndrome induced by adjuvants Silicone has been widely used in the manufacture of medical implants. It is well tolerated in most cases. However, in this paper, we report the cases of three women who developed autoimmune/inflammatory syndrome induced by adjuvants (ASIA syndrome), namely with silicone breast implants.

Rheumatoid Arthritis

Rheumatoid arthritis is a chronic inflammatory disorder that can affect more than just your joints. In some people, the condition can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels.

Heavy Metal Toxicity

Metal toxicity or ” metal poising”, is the toxic effect of certain metals in certain forms. Not all heavy metals are particularly toxic, and some are essential, such as iron. Autoimmunity in our new world stems from an overload of chemical toxicity in our food, water, environment, Cell phones, People and our daily lifestyle.

Heal Your Gut

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Lyme Disease

Many over the counter NSAID medications like naproxen, ibuprofen, and aspirin are very hard on your kidneys. Always make sure to follow the dosages on the bottle and also to eat with food and drink plenty of water when you are on these medications to ease the impact on your stomach and renal system.

Electro Magnetic Frequencies

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Prescription Drugs

Many over the counter NSAID medications like naproxen, ibuprofen, and aspirin are very hard on your kidneys. Always make sure to follow the dosages on the bottle and also to eat with food and drink plenty of water when you are on these medications to ease the impact on your stomach and renal system.

Epstein Barr

Have you had mono, Steph, multiple times? The Epstein-Barr Virus (EBV) also called human herpesvirus 4 (HHV-4), is one of the eight viruses in the herpes family. EBV is very contagious and remains in the body, mainly in the white cells, for life. Learn how to keep this co-infection dormant with proper food herbs and integrative energy work.

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Medically Challenged Community
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